First name and surname                                                    Thomas Singer
Date of birth                                                                     April 4, 1960
Place of birth                                                                    Schwandorf
Nationality                                                                        German

Education 

1978	Study of Biotechnology Science, University of Munich, Weihenstephan
1982	Dipl. Ing. agr. (M.Sc.)
1983-1988	Faculty of Veterinary Medicine Ludwig-Maximilian University of Munich (D.V.M.)
1989	Ph.D. thesis: Deoxyspergualin, a New Immunosuppressive Regimen in Xenogeneic Organ Transplantation (Dr. med. vet.)
1993	Veterinary Board Certification for Toxicology (FVH, Spezialtierarzt für Grundlagenmedizin und Toxikologie, CH)
1994	Certified Diplomate of the American Board of Toxicology, DABT
1996	Veterinary Board Certification for Pharmacology and Toxicology (Fachtierarzt für Pharmakologie und Toxikologie)
2003	Fellow Pembroke College, Cambridge, UK

Employment history 

2004	Global Deputy Head Non Clinical Development Roche Pharma AG (TRD small and macro molecules)
2004	Head of the Roche Holding Biotherapeutic Workgroup. Scope early development of biotherapeutics with regard to safety, regulatory and API. Development of company holding wide guidelines to harmonize protein development within the Roche Holding (Roche, Chugai, Genentech) according to the most current regulatory standards and impacting health authority regulations.
2003	Appointment to Senior Vice President
1999 - 2003	European Liaison Officer of the American Board of Toxicology
2002	Global Head of Non Clinical Safety at F. Hoffmann-La Roche Ltd., Basel
2000	Chair of the Boehringer Ingelheim Safety Committee
1998	Head of Department of Nonclinical Drug Safety at Boehringer Ingelheim Pharma KG, Biberach
1997	Scientific Deputy Head of the Department TOX/PATH Novartis AG
1996	Member of Integration Team Drug Safety Sandoz/Ciba to form Novartis
1995	Deputy Head of Toxicology, Sandoz Pharma Ltd.
1992	Head of General Toxicology, Sandoz. Pharma Ltd., Department of Drug Safety.
1989	Sandoz Pharma Ltd., Department of Drug Safety

Membership of Roche Management Boards

RDC - Research and Development Committee
Chair J. Knowles, member of the Roche Executive Committee and Head of Global Research
Permanent and full membership since 2002

LCC - Life Cycle Committee
Chair W. Burns, CEO Division Roche Pharmaceuticals
Scope Late Stage Development and Marketing
Ad hoc membership since 2002

DSC - Drug Safety Committee
Chair E. Holdener, Head Global Pharmaceutical Drug Development
Full membership since 2002

NC - DSC - Non Clinical - Drug Safety Committee
Chair and full member
Scope Preclinical and Early Clinical Safety. Responsibility for Global Safety issues and for recommendations for dose level selections in the subsequent Phase I and Phase II clinical trials.

RMT - Research Management Team
Chair J. Knowles
Full membership since 2003

STS - Safety and Technical Science Management Team
Co-Chair and full member since 2002

Scientific Review Board Roche Holding
Chugai Japan, Palo Alto, Nutley, Basel, Penzberg
Full member

TPI - Therapeutic Protein Initiative
Full member and advisor

RMM - Roche Management Meeting
Chair F. Humer, Chairman Roche Board of Directors.
Full member since 2002.
 
Contributions to Research and Development performance
11 NDA’s
88 IND/CTA’s
1 world wide patent

Awards 
2 Roche Olympiad medals for the safety organization
granted in March 2006 by W. Burns, CEO Pharmaceuticals Division
Global Laboratory Information Management System Program (GLIMS)

Investigative Rat Toxicology Studies to elucidate the mechanism of peripheral neuropathy
 
Memberships of scientific societies

• Society for Veterinary Pathology
• Society of Toxicologic Pathologists (USA)
• Deutsche Veterinärmedizinische Gesellschaft (DVG)
• Fachgruppe Allgemeine Pathologie und Pathologische Anatomie
• Eurotox member
• Full Member of the Society of Toxicology (SOT)
• European Liaison of the American Board of Toxicology
• EFPIA Working Party Safety AHG
• British Society of Toxicology

Pembroke College Cambridge
William Pit Fellow

Thomas Singer - April 20th  2006